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ADPRM Polyklonaler Antikörper

ADPRM Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17017-1-PBS

Synonyme

C17orf48, ADPRibase Mn, ADPRibase-Mn, ADP-Ribose/CDP-Alcohol Diphosphatase, Manganese Dependent, CDP choline phosphohydrolase

Filter:
  • Western Blot (WB) analysis of various lysates using ADPRM Polyclonal antibody (17017-1-AP)

    WB analysis using 17017-1-AP (same clone as 17017-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17017-1-AP (C17orf48 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17017-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17017-1-PBS bindet in WB, Indirect ELISA ADPRM und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ADPRM fusion protein Ag9997
Vollständiger Name chromosome 17 open reading frame 48
Berechnetes Molekulargewicht 40 kDa
Beobachtetes Molekulargewicht45 kDa
GenBank-ZugangsnummerBC001294
Gene symbol C17orf48
Gene ID (NCBI) 56985
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese dependent) is a manganese-dependent glycophosphatase primarily responsible for the breakdown of molecules such as ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine in the cell. The protein is predicted to be located in the cytoplasm and possesses 2',3'-cyclic nucleotide 2'-phosphodiesterase activity, manganese ion-binding activity, and pyrophosphatase activity. ADPRM plays an important role in embryonic development, particularly in the formation of the heart and lungs. In addition, ADPRM may be involved in immune cell signaling, acting as a second messenger for ADP-ribose to activate TRPM2, which in turn regulates oxidative/nitrosative stress.