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ADRB3 Polyklonaler Antikörper

ADRB3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30713-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using ADRB3 Polyclonal antibody (30713-1-AP)

    WB analysis using 30713-1-AP (same clone as 30713-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30713-1-AP (ADRB3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30713-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30713-1-PBS bindet in WB, Indirect ELISA ADRB3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ADRB3 fusion protein Ag31466
Vollständiger Name adrenergic, beta-3-, receptor
Berechnetes Molekulargewicht 44 kDa
Beobachtetes Molekulargewicht44-50 kDa
GenBank-ZugangsnummerNM_000025
Gene symbol ADRB3
Gene ID (NCBI) 155
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Beta-3 adrenergic receptor(ADRB3), a member of the G-protein-coupled receptor family, is expressed mainly in adipose tissue and is thought to contribute to lipolysis and thermogenesis. In addition, the overexpression of ADRB3 has been found in several cancer types, including breast cancer, gallbladder cancer , and colorectal cancer. More recently, the involvement of ADRB3 in the metabolic reprogramming of melanoma, the promotion of immune tolerance, and the regulation of cancer differentiation have been described. (PMID: 32514619)