ADRM1 Monoklonaler Antikörper
ADRM1 Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA
Wirt / Isotyp
Maus / IgG3
Getestete Reaktivität
human
Anwendung
WB, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
1A1A3
Kat-Nr. : 66464-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66464-1-PBS bindet in WB, IF/ICC, Indirect ELISA ADRM1 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG3 |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | ADRM1 fusion protein Ag24699 |
| Vollständiger Name | adhesion regulating molecule 1 |
| Berechnetes Molekulargewicht | 407 aa, 42 kDa |
| Beobachtetes Molekulargewicht | 42 kDa |
| GenBank-Zugangsnummer | BC017245 |
| Gene symbol | ADRM1 |
| Gene ID (NCBI) | 11047 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
The 26S proteasome is a key component of the ubiquitin-proteasome system, a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme, UCH37, and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.



