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ADSL Rekombinanter Antikörper

ADSL Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250216C6

Kat-Nr. : 86131-1-PBS

Synonyme

AMPS, ASASE, ASL, EC:4.3.2.2

Filter:
  • Western Blot (WB) analysis of various lysates using ADSL Recombinant monoclonal antibody (86131-1-RR)

    WB analysis using 86131-1-RR (same clone as 86131-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86131-1-RR (ADSL antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86131-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86131-1-RR

    Affinity and Kinetic Characterization of 86131-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86131-1-RR against Human ADSL were performed. The affinity constant is 4.05 nM.

Geprüfte Anwendungen

Produktinformation

86131-1-PBS bindet in WB, Indirect ELISA ADSL und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ADSL fusion protein Ag7332
Vollständiger Name adenylosuccinate lyase
Berechnetes Molekulargewicht 55 kDa
Beobachtetes Molekulargewicht 55 kDa
GenBank-ZugangsnummerBC000253
Gene symbol ADSL
Gene ID (NCBI) 158
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Adenylosuccinate lyase (ADSL) is an essential enzyme for de novo purine biosynthesis and the purine nucleotide cycle, where it plays a key role in the regulation of adenosine monophosphate levels in the cells. Given its crucial role in both cellular replication and metabolism, it is not surprising that ADSL has been found dysregulated in several malignancies, including breast and endometrial cancers as well as glioma. (PMID: 33754045)