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AES Polyklonaler Antikörper

AES Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23913-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using AES Polyclonal antibody (23913-1-AP)

    WB analysis using 23913-1-AP (same clone as 23913-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23913-1-AP (AES antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23913-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

23913-1-PBS bindet in WB, Indirect ELISA AES und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen AES fusion protein Ag21021
Vollständiger Name amino-terminal enhancer of split
Berechnetes Molekulargewicht 264 aa, 29 kDa
Beobachtetes Molekulargewicht 22-29 kDa
GenBank-ZugangsnummerBC113735
Gene symbol AES
Gene ID (NCBI) 166
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Amino-terminal enhancer of split (AES), belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members in order to forcefully repress the expression of other family member genes. AES can repress NFkB-regulated gene expression and is believed to have a significant role in initiating and maintaining cell differentiation events. AES has been found to suppress local invasion and intravasation through inhibition of the Notch pathway, leading to preventing the metastatic spread of endogenous tumors(PMID: 33754069).