AGGF1 Rekombinanter Antikörper

AGGF1 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

242264E9

Kat-Nr. : 84715-3-RR

Synonyme

242264E9, Angiogenic factor VG5Q, G patch domain-containing protein 7, GPATC7, GPATCH7

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  WB analysis using 84715-3-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84715-3-RR (AGGF1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 84715-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84715-3-RR against Human AGGF1 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HEK-293-Zellen, HCT 116-Zellen, HeLa-Zellen, L02-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

84715-3-RR bindet in WB, ELISA AGGF1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: AGGF1 fusion protein Ag2497
• Vollständiger Name: angiogenic factor with G patch and FHA domains 1
• Berechnetes Molekulargewicht: 714 aa, 81 kDa
• Beobachtetes Molekulargewicht: 84-100 kDa
• GenBank-Zugangsnummer: BC029382
• Gene symbol: AGGF1
• Gene ID (NCBI): 55109
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.