AGXT2L1 Rekombinanter Antikörper

AGXT2L1 Rekombinant Antikörper für IHC, IF/ICC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, IF/ICC, ELISA

Konjugation

Unkonjugiert

CloneNo.

241119H5

Kat-Nr. : 83984-5-PBS

Synonyme

ETNPPL, Ethanolamine-phosphate phospho-lyase, EC:4.2.3.2, Alanine--glyoxylate aminotransferase 2-like 1, 241119H5

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  IHC staining of mouse liver using 83984-5-RR (same clone as 83984-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 83984-5-RR (AGXT2L1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83984-5-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 83984-5-RR (same clone as 83984-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 83984-5-RR (AGXT2L1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83984-5-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 83984-5-RR (same clone as 83984-5-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using AGXT2L1 antibody (83984-5-RR, Clone: 241119H5 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 83984-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83984-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83984-5-RR against Human AGXT2L1 were performed. The affinity constant is 1.77 nM.

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Geprüfte Anwendungen

Produktinformation

83984-5-PBS bindet in IHC, IF/ICC, ELISA AGXT2L1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: AGXT2L1 fusion protein Ag10584
• Vollständiger Name: alanine-glyoxylate aminotransferase 2-like 1
• Berechnetes Molekulargewicht: 499 aa, 56 kDa
• GenBank-Zugangsnummer: BC022526
• Gene symbol: AGXT2L1
• Gene ID (NCBI): 64850
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Alanine-glyoxylate aminotransferase 2-like 1 (AGXT2L1), also called ethanolamine phosphate phospholyase (ETNPPL), is a brain enzyme, so-named after its similarity to AGXT2 (36% sequence identity), that may be involved in the pathogenesis of severe neuropsychiatric disturbances(PMID: 23761375). AGXT2L1 is significantly down-regulated in cancerous tissues and may be a tumor suppressor(PMID: 26294768,