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ALAD Polyklonaler Antikörper

ALAD Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31686-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using ALAD Polyclonal antibody (31686-1-AP)

    WB analysis using 31686-1-AP (same clone as 31686-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31686-1-AP (ALAD antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31686-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31686-1-PBS bindet in WB, Indirect ELISA ALAD und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ALAD fusion protein Ag35649
Vollständiger Name aminolevulinate, delta-, dehydratase
Berechnetes Molekulargewicht36kDa，330aa
Beobachtetes Molekulargewicht 36-39 kDa
GenBank-ZugangsnummerNM_000031.5
Gene symbol ALAD
Gene ID (NCBI) 210
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Delta-aminolevulinic acid dehydratase (ALAD) is also named as Porphobilinogen synthase. ALAD, encoded by the moonlighting gene ALAD, not only participates in the second step of heme biosynthesis, but also inhibits the 26S proteasome (PMID: 35318110). ALAD is involved in tumor progression. For example, ALAD2 allele (ALAD polymorphism) is related to an increased risk for meningioma, and downregulation of ALAD is related to poor prognosis of patients with breast cancer (PMID: 16140629, PMID: 28403546).