ALDH2 Monoklonaler Antikörper

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ALDH2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Hausschwein, human, Kaninchen, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2G10F4

Kat-Nr. : 68237-1-PBS

Synonyme

ALDH class 2, ALDH E2, ALDH2, ALDHI, ALDM

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  WB analysis of mouse liver using 68237-1-Ig (same clone as 68237-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 68237-1-Ig (ALDH2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

• 

  WB analysis of pig liver using 68237-1-Ig (same clone as 68237-1-PBS)

  pig liver tissue were subjected to SDS PAGE followed by western blot with 68237-1-Ig (ALDH2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 68237-1-Ig (same clone as 68237-1-PBS)

  WB result of ALDH2 antibody (68237-1-Ig; 1:10000; incubated at room temperature for 1.5 hours) with sh-Control and sh-ALDH2 transfected HepG2 cells. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rabbit liver using 68237-1-Ig (same clone as 68237-1-PBS)

  rabbit liver tissue were subjected to SDS PAGE followed by western blot with 68237-1-Ig (ALDH2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat liver using 68237-1-Ig (same clone as 68237-1-PBS)

  rat liver tissue were subjected to SDS PAGE followed by western blot with 68237-1-Ig (ALDH2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68237-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68237-1-PBS bindet in WB, Indirect ELISA ALDH2 und zeigt Reaktivität mit Hausschwein, human, Kaninchen, Maus, Ratten

• Getestete Reaktivität: Hausschwein, human, Kaninchen, Maus, Ratte
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: ALDH2 fusion protein Ag7463
• Vollständiger Name: aldehyde dehydrogenase 2 family (mitochondrial)
• Berechnetes Molekulargewicht: 56 kDa
• Beobachtetes Molekulargewicht: 50-55 kDa
• GenBank-Zugangsnummer: BC002967
• Gene symbol: ALDH2
• Gene ID (NCBI): 217
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease.