AMH Rekombinanter Antikörper

AMH Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241148C8

Kat-Nr. : 84153-5-PBS

Synonyme

Muellerian inhibiting factor, Anti-Muellerian hormone (AMH), Anti-Muellerian hormone, anti Mullerian hormone, Anti muellerian hormone

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  WB analysis using 84153-5-RR (same clone as 84153-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84153-5-RR (AMH antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84153-5-PBS in a different storage buffer formulation.

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  IHC staining of human ovary cancer using 84153-5-RR (same clone as 84153-5-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 84153-5-RR (AMH antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84153-5-PBS in a different storage buffer formulation.

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  IHC staining of human ovary cancer using 84153-5-RR (same clone as 84153-5-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 84153-5-RR (AMH antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84153-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84153-5-RR

  Biolayer interferometry (BLl) kinetic assays of 84153-5-RR against Human AMH were performed. The affinity constant is 2.16 nM.

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Geprüfte Anwendungen

Produktinformation

84153-5-PBS bindet in WB, IHC, Indirect ELISA AMH und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: AMH fusion protein Ag5670
• Vollständiger Name: anti-Mullerian hormone
• Berechnetes Molekulargewicht: 59 kDa
• Beobachtetes Molekulargewicht: 60-65 kDa
• GenBank-Zugangsnummer: BC049194
• Gene symbol: AMH
• Gene ID (NCBI): 268
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Anti-Müllerian hormone (AMH), also called Müllerian-inhibiting substance (MIS), is a hormone that is best known for its production by fetal testes in mammals and as the inhibitor of Müllerian duct development in males. AMH is also expressed in granulosa cells of preantral and small antral follicles in the ovary. More recently, AMH has been studied for its role in ovarian folliculogenesis and as a potential marker of ovarian reserve. The deduced protein sequence of the AMH monomer contains a 25 amino acid secretion specific signal peptide and a monomeric protein of 535 amino acids that, when glycosylated at two glycosylation sites, has a molecular weight of 65-70 kDa.