AMOTL1 Polyklonaler Antikörper

AMOTL1 Polyklonal Antikörper für WB,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

4

Kat-Nr. : 16871-1-AP

Synonyme

AMOTL1, angiomotin like 1, Angiomotin like protein 1, JEAP

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Galerie der Validierungsdaten

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  WB analysis of HeLa using 16871-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 16871-1-AP (AMOTL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HeLa using 16871-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 16871-1-AP (AMOTL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HeLa-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 4 publications below
• IF: See 2 publications below

Produktinformation

16871-1-AP bindet in WB, IF, ELISA AMOTL1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: angiomotin like 1
• Berechnetes Molekulargewicht: 107 kDa
• Beobachtetes Molekulargewicht: 107 kDa
• GenBank-Zugangsnummer: NM_130847
• Gene symbol: AMOTL1
• Gene ID (NCBI): 154810
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.

Publikationen

Species	Application	Title
human	WB	Curr Biol; Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.; Authors - Anna Ulbricht
human	WB	Environ Toxicol; Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.; Authors - Gang Xu
mouse	WB,IF	Pulm Pharmacol Ther; Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.; Authors - Rioto Suzuki
human	WB,IF	Cell Death Dis; SRSF3/AMOTL1 splicing axis promotes the tumorigenesis of nasopharyngeal carcinoma through regulating the nucleus translocation of YAP1; Authors - Xiao-Chen Xu