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Angiopoietin 1 Polyklonaler Antikörper
Angiopoietin 1 Polyklonal Antikörper für WB, IF/ICC, ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte und mehr (1)
Anwendung
WB, IF/ICC, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 23302-1-AP
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in WB | HUVEC-Zellen, A375-Zellen, C6-Zellen, HeLa-Zellen, HepG2-Zellen, K-562-Zellen, Mausherzgewebe, Mauslebergewebe, Rattenherzgewebe, U-87 MG-Zellen |
| Erfolgreiche Detektion in IF/ICC | HeLa-Zellen |
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunfluoreszenz (IF)/ICC | IF/ICC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Veröffentlichte Anwendungen
| KD/KO | See 1 publications below |
| WB | See 31 publications below |
| IF | See 4 publications below |
Produktinformation
23302-1-AP bindet in WB, IF/ICC, ELISA Angiopoietin 1 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| In Publikationen genannte Reaktivität | human, Kaninchen, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | Angiopoietin 1 fusion protein Ag18829 |
| Vollständiger Name | angiopoietin 1 |
| Berechnetes Molekulargewicht | 498 aa, 58 kDa |
| Beobachtetes Molekulargewicht | 70 kDa |
| GenBank-Zugangsnummer | BC152411 |
| Gene symbol | Angiopoietin 1 |
| Gene ID (NCBI) | 284 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Angiopoietin 1 is a 70-kDa secreted glycoprotein generated from vascular mural cells, pericytes, and certain other cells. Angiopoietin 1 participates in vascular differentiation through angiogenesis, which is the process of the growth and remodelling of existing vessels. Angiopoietin 1 is also involved in the maintenance and turnover of blood vessels in mature animals. Angiopoietin 1 binds to and activates the TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation, playing an important role in the regulation of angiogenesis. Overexpression of Angiopoietin 1 has been proven to occur in malignant glioblastoma, neuroblastoma, non-small cell lung cancer, and other tumors.
Protokolle
| PRODUKTSPEZIFISCHE PROTOKOLLE | |
|---|---|
| WB protocol for Angiopoietin 1 antibody 23302-1-AP | Protokoll herunterladen |
| IF protocol for Angiopoietin 1 antibody 23302-1-AP | Protokoll herunterladen |
| STANDARD-PROTOKOLLE | |
|---|---|
| Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
| Species | Application | Title |
|---|---|---|
Biomater Res High yield engineered nanovesicles from ADSC with enriched miR-21-5p promote angiogenesis in adipose tissue regeneration | ||
Acta Biomater Chemotactic Recruitment of Genetically Engineered Cell Membrane-Camouflaged Metal-Organic Framework Nanoparticles for Ischemic Osteonecrosis Treatment | ||
Mol Ther Nucleic Acids Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC. | ||
Neural Regen Res Endorepellin downregulation promotes angiogenesis after experimental traumatic brain injury | ||
J Cell Mol Med IGFBP-4 enhances VEGF-induced angiogenesis in a mouse model of myocardial infarction. | ||
Br J Pharmacol Canonical hedgehog signaling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis. |






