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ANTXR2 Polyklonaler Antikörper
ANTXR2 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, IHC, IP, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 16723-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
16723-1-PBS bindet in WB, IHC, IP, Indirect ELISA ANTXR2 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | ANTXR2 fusion protein Ag10162 |
| Vollständiger Name | anthrax toxin receptor 2 |
| Berechnetes Molekulargewicht | 54 kDa |
| Beobachtetes Molekulargewicht | 55 kDa |
| GenBank-Zugangsnummer | BC107876 |
| Gene symbol | ANTXR2 |
| Gene ID (NCBI) | 118429 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
ANTXR2 (anthrax toxin receptor 2), also known as CMG2 (capillary morphogenesis gene 2 protein) is a transmembrane protein that is induced during capillary morphogenesis. It contains a vWA domain that shows strong binding to laminin and collagen IV, suggesting that this protein plays a role in basement membrane matrix assembly and endothelial cell morphogenesis (PMID: 11683410; 14508707). Like its paralog TEM8 (ANTXR1), ANTXR2 also functions as a receptor for anthrax toxin. Mutations in ANTXR2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis (PMID: 14508707; 12973667; 22383261).

























