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ANXA8 Polyklonaler Antikörper

ANXA8 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33144-1-PBS

Synonyme

Annexin A8, Annexin VIII, Annexin-8, ANX8, VAC-beta

Filter:
  • Western Blot (WB) analysis of various lysates using ANXA8 Polyclonal antibody (33144-1-AP)

    WB analysis using 33144-1-AP (same clone as 33144-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33144-1-AP (ANXA8 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33144-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33144-1-PBS bindet in WB, Indirect ELISA ANXA8 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ANXA8 fusion protein Ag39741
Vollständiger Name annexin A8
Berechnetes Molekulargewicht 36 kDa
Beobachtetes Molekulargewicht35 kDa
GenBank-ZugangsnummerBC073755
Gene symbol ANXA8
Gene ID (NCBI) 653145
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Annexin A8 (ANXA8) gene, a member of the annexin family, encodes an anticoagulant protein involved in blood coagulation cascade and acts as an indirect inhibitor of the thromboplastin-specific complex. ANXA8 promotes the proliferation of endometrial cells through the Akt signalling pathway (PMID: 30040162). The expression levels of multiple cellular factors, including EGFR, PI3K, Akt, mTOR, p70S6K and 4EBP1, in the epidermal growth factor receptor (EGFR) signaling pathway were also altered by ANXA8 knockdown or overexpression in A549 cells, which confirmed the activation of the EGFR/Akt/mTOR signaling pathway by ANXA8 (PMID: 34671007).