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AP4B1 Polyklonaler Antikörper

AP4B1 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16313-1-PBS

Synonyme

Beta4-adaptin, Beta subunit of AP-4, AP-4 complex subunit beta-1, AP-4 adaptor complex subunit beta, Adaptor-related protein complex 4 subunit beta-1

Filter:
  • Western Blot (WB) analysis of various lysates using AP4B1 Polyclonal antibody (16313-1-AP)

    WB analysis using 16313-1-AP (same clone as 16313-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16313-1-AP (AP4B1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16313-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of HeLa cells using AP4B1 Polyclonal antibody (16313-1-AP)

    IP experiment of HeLa using 16313-1-AP (same clone as 16313-1-PBS)

    IP result of anti-AP4B1 (IP:16313-1-AP, 4ug; Detection:16313-1-AP 1:300) with HeLa cells lysate 3200ug. This data was developed using the same antibody clone with 16313-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

16313-1-PBS bindet in WB, IP, Indirect ELISA AP4B1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen AP4B1 fusion protein Ag9348
Vollständiger Name adaptor-related protein complex 4, beta 1 subunit
Berechnetes Molekulargewicht 739 aa, 83 kDa
Beobachtetes Molekulargewicht75-83 kDa
GenBank-ZugangsnummerBC014146
Gene symbol AP4B1
Gene ID (NCBI) 10717
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Adaptor protein (AP) complex is a component of intracellular protein transport. The AP4 complex is involved in sorting transmembrane cargo proteins into transport vesicles for trans-Golgi network export. AP4B1 is a member of the AP4 complex, which also includes AP4E1, AP4M1 and AP4S1. Loss-of-function variants in any of these four members can lead to AP-4-associated hereditary spastic paraplegia (HSP), a neurodegenerative disorder (PMID: 30543385). This antibody recognizes AP4B1.