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APOB48R Polyklonaler Antikörper

APOB48R Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25328-1-PBS

Synonyme

apoB 48R, apoB-48R, APOBR, Apolipoprotein B 100 receptor, Apolipoprotein B 48 receptor

Filter:
  • Western Blot (WB) analysis of various lysates using APOB48R Polyclonal antibody (25328-1-AP)

    WB analysis using 25328-1-AP (same clone as 25328-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25328-1-AP (APOB48R antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25328-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25328-1-PBS bindet in WB, Indirect ELISA APOB48R und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen APOB48R fusion protein Ag18204
Vollständiger Name apolipoprotein B48 receptor
Berechnetes Molekulargewicht 1088 aa, 116 kDa
Beobachtetes Molekulargewicht116 kDa
GenBank-ZugangsnummerBC119786
Gene symbol APOB48R
Gene ID (NCBI) 55911
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Apolipoprotein B48 receptor (APOB48R) is a macrophage receptor that binds to apoB of dietary triglyceride-rich lipoproteins or to a similar apoB-like domain in hypertriglyceridemic very low-density lipoprotein (HTG-VLDL). This receptor is crucial for the uptake of chylomicrons, HTG-VLDL, and trypsinized VLDL lacking apoE in macrophages. APOB48R may contribute necessary lipids, lipid-soluble vitamins, and other nutrients to reticuloendothelial cells. Elevated plasma triglyceride levels may cause APOB48R to be a factor in foam cell formation, endothelial dysfunction, and atherothrombogenesis (PMID: 10852956; 9633939; 15591219).