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APOBEC1 Polyklonaler Antikörper

APOBEC1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32857-1-PBS

Synonyme

APO1, APOBEC-1, Apolipoprotein B mRNA-editing enzyme 1, Apolipoprotein B mRNA-editing enzyme catalytic subunit 1, C->U-editing enzyme APOBEC-1

Filter:
  • Western Blot (WB) analysis of various lysates using APOBEC1 Polyclonal antibody (32857-1-AP)

    WB analysis using 32857-1-AP (same clone as 32857-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32857-1-AP (APOBEC1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32857-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32857-1-PBS bindet in WB, Indirect ELISA APOBEC1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen APOBEC1 fusion protein Ag26715
Vollständiger Name apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Berechnetes Molekulargewicht 28 kDa
Beobachtetes Molekulargewicht25 kDa
GenBank-ZugangsnummerNM_001304566
Gene symbol APOBEC1
Gene ID (NCBI) 339
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Apolipoprotein B mRNA-editing enzyme catalytic subunit 1 (APOBEC1) is a member of the cytidine deaminase enzyme family. It forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP) (PMID: 30844405). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs (PMID: 24916387; 11727199). APOBEC1 plays a crucial role in RNA editing, which is essential for the proper function of these proteins. Additionally, APOBEC1 has been implicated in various cellular processes, including the regulation of gene expression and the maintenance of genomic stability (PMID: 33094286).