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APOBEC3A Polyklonaler Antikörper

APOBEC3A Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25084-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using APOBEC3A Polyclonal antibody (25084-1-AP)

    WB analysis using 25084-1-AP (same clone as 25084-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25084-1-AP (APOBEC3A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25084-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of THP-1 cells using APOBEC3A Polyclonal antibody (25084-1-AP)

    IF Staining of THP-1 using 25084-1-AP (same clone as 25084-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using APOBEC3A antibody (25084-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 25084-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25084-1-PBS bindet in WB, IF/ICC, Indirect ELISA APOBEC3A und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen APOBEC3A fusion protein Ag18845
Vollständiger Name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
Berechnetes Molekulargewicht 199 aa, 23 kDa
Beobachtetes Molekulargewicht23 kDa
GenBank-ZugangsnummerBC126416
Gene symbol APOBEC3A
Gene ID (NCBI) 200315
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

APOBEC3A, also known as A3A, belongs to the cytidine and deoxycytidylate deaminase family. APOBEC3A plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. APOBEC3A is expressed in several cell types, including keratinocytes and myeloid cells (PMID: 28825669). APOBEC3A has 2 isoforms with the molecular mass of 22 and 23 kDa.