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APOE Monoklonaler Antikörper
APOE Monoklonal Antikörper für WB, IF/ICC, FC (Intra), ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human
Anwendung
WB, IF/ICC, FC (Intra), ELISA
Konjugation
Unkonjugiert
CloneNo.
1B2C9
Kat-Nr. : 66830-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66830-1-PBS bindet in WB, IF/ICC, FC (Intra), ELISA APOE und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | APOE fusion protein Ag28186 |
Vollständiger Name | Apolipoprotein E |
Berechnetes Molekulargewicht | 36 kDa |
Beobachtetes Molekulargewicht | 34-36 kDa |
GenBank-Zugangsnummer | BC003557 |
Gene symbol | APOE |
Gene ID (NCBI) | 348 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
The apolipoprotein E (APOE) is a 299-amino acid polypeptide that mediates the binding, internalization, and catabolism of lipoprotein particles, and also serve as a ligand for the LDL (APO B/E) receptor and for the specific APOE receptor (chylomicron remnant) of hepatic tissues. The very strong association of the APOE ɛ4 allele with AD risk and its role in the accumulation of amyloid β in brains of people and animal models solidify the biological relevance of APOE isoforms but do not provide mechanistic insight.