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APP Monoklonaler Antikörper

APP Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Hausschwein, human, Kaninchen, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

5C2A1

Kat-Nr. : 60342-1-PBS

Synonyme

amyloid precursor protein, Alzheimer disease amyloid A4 protein homolog, AD1, AB42, AB40



Geprüfte Anwendungen

Produktinformation

60342-1-PBS bindet in WB, IHC, Indirect ELISA APP und zeigt Reaktivität mit Hausschwein, human, Kaninchen, Ratten

Getestete Reaktivität Hausschwein, human, Kaninchen, Ratte
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen APP fusion protein Ag0769
Vollständiger Name amyloid beta (A4) precursor protein
Berechnetes Molekulargewicht 87 kDa
Beobachtetes Molekulargewicht 100 kDa
GenBank-ZugangsnummerBC004369
Gene symbol APP
Gene ID (NCBI) 351
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Aβ derives from APP via proteolytic cleavage by proteases called α-, β- and γ-secretase. The α-secretase cleavage precludes the formation of Aβ, while the β- and γ-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1).