APPBP2 Polyklonaler Antikörper

APPBP2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12409-1-PBS

Synonyme

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  WB analysis using 12409-1-AP (same clone as 12409-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12409-1-AP (APPBP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 12409-1-AP (same clone as 12409-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12409-1-AP (APPBP2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 12409-1-AP (same clone as 12409-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 12409-1-AP (APPBP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). Chromogenic substrates are DAB/H2O2 and CuSO4. This data was developed using the same antibody clone with 12409-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

12409-1-PBS bindet in WB, IHC, Indirect ELISA APPBP2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: APPBP2 fusion protein Ag3092
• Vollständiger Name: amyloid beta precursor protein (cytoplasmic tail) binding protein 2
• Berechnetes Molekulargewicht: 585 aa, 67 kDa
• Beobachtetes Molekulargewicht: 67 kDa
• GenBank-Zugangsnummer: BC018121
• Gene symbol: APPBP2
• Gene ID (NCBI): 10513
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Amyloid proteinbinding protein 2 (APPBP2) is a hydrophilic tubulin that interacts with microtubules and is functionally involved in beta-amyloid precursor protein (APP) transport and/or processing. Based on the regulation of microtubules and APP, APPBP2 is found to be involved in the oncogenesis of various types of cancers, such as breast cancer, ovarian clear cell adenocarcinomas, desmoplastic medulloblastomas and neuroblastomas. Recently, Studies have demonstrated that APPBP2 is a potential target for diagnosis and therapeutic intervention in non-small cell lung cancer (NSCLC) (PMID: 31105033).