ARAP3 Polyklonaler Antikörper
ARAP3 Polyklonal Antikörper für IHC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
IHC, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 22578-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
22578-1-PBS bindet in IHC, Indirect ELISA ARAP3 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | ARAP3 fusion protein Ag17436 |
| Vollständiger Name | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| Berechnetes Molekulargewicht | 1544 aa, 170 kDa |
| GenBank-Zugangsnummer | BC009968 |
| Gene symbol | ARAP3 |
| Gene ID (NCBI) | 64411 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins are best characterized as regulators of membrane traffic. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. ARAP3 (Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3) is unique for its dual specificity GAPs (GTPase activating protein) activity for Arf6 (ADP-ribosylation factor 6) and RhoA (Ras homolog gene family member A) regulated by PtdIns(3,4,5)P3 (phosphatidylinositol (3,4,5)-trisphosphate) and a small GTPase Rap1-GTP and is involved in regulation of cell shape and adhesion.







