ARHGAP10 Polyklonaler Antikörper

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ARHGAP10 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55139-1-PBS

Synonyme

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  WB analysis of mouse heart using 55139-1-AP (same clone as 55139-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse kidney using 55139-1-AP (same clone as 55139-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 55139-1-AP (same clone as 55139-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 55139-1-AP (ARHGAP10 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart using 55139-1-AP (ARHGAP10 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 55139-1-AP (same clone as 55139-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

55139-1-PBS bindet in WB, IHC, Indirect ELISA ARHGAP10 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: Rho GTPase activating protein 10
• Berechnetes Molekulargewicht: 89 kDa
• Beobachtetes Molekulargewicht: 89 kDa
• GenBank-Zugangsnummer: NM_024605
• Gene symbol: ARHGAP10
• Gene ID (NCBI): 79658
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ARHGAP10, also named as GRAF2, is GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. It is essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. ARHGAP10 inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. It stabilizes PAK-2p34 thereby increasing stimulation of cell death. The antibody is specific to ARHGAP10.