ARHGAP23 Polyklonaler Antikörper

ARHGAP23 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31938-1-PBS

Synonyme

KIAA1501, Rho GTPase Activating Protein 23, Rho GTPase-activating protein 23, Rho-type GTPase-activating protein 23

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  WB analysis using 31938-1-AP (same clone as 31938-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31938-1-AP (ARHGAP23 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31938-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 31938-1-AP (same clone as 31938-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 31938-1-AP (ARHGAP23 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31938-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 31938-1-AP (same clone as 31938-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 31938-1-AP (ARHGAP23 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31938-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

31938-1-PBS bindet in WB, IHC, Indirect ELISA ARHGAP23 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ARHGAP23 fusion protein Ag36340
• Vollständiger Name: Rho GTPase activating protein 23
• Berechnetes Molekulargewicht: 162kDa
• Beobachtetes Molekulargewicht: 140-150 kDa
• GenBank-Zugangsnummer: NM_001199417
• Gene symbol: ARHGAP23
• Gene ID (NCBI): 57636
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ARHGAP23 (Rho GTPase Activating Protein 23) belongs to the family of Rho GTPase activating proteins. The protein functions as a GTPase-activating factor by converting Rho class GTPases into their inactive GDP-bound state. ARHGAP23 is involved in the Rho GTPase signaling pathway, affecting processes such as cytoskeletal reorganization, cell migration, and cell proliferation. In non-small cell lung cancer, the expression of ARHGAP23 is associated with tumor immune infiltration and prognosis, and its role in tumor development has attracted attention. Mutations in this gene are related to a variety of diseases, including certain types of cancer and neurological disorders.