ARHGEF4 Polyklonaler Antikörper

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• KD/KO Validated

ARHGEF4 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55213-1-PBS

Synonyme

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  WB analysis of mouse brain using 55213-1-AP (same clone as 55213-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 55213-1-AP (ARHGEF4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

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  WB analysis of multi-cells/tissue using 55213-1-AP (same clone as 55213-1-PBS)

  WB result of 55213-1-AP (ARHGEF4 Antibody). This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 55213-1-AP (same clone as 55213-1-PBS)

  IP result of anti-ARHGEF4 (IP:55213-1-AP, 4ug; Detection:55213-1-AP 1:1000) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 55213-1-AP (same clone as 55213-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 55213-1-AP (ARHGEF4 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human brain using 55213-1-AP (same clone as 55213-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 55213-1-AP (ARHGEF4 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 55213-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

55213-1-PBS bindet in WB, IHC, IP, Indirect ELISA ARHGEF4 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: Rho guanine nucleotide exchange factor (GEF) 4
• Berechnetes Molekulargewicht: 79 kDa
• Beobachtetes Molekulargewicht: 72 kDa
• GenBank-Zugangsnummer: NM_015320
• Gene symbol: ARHGEF4
• Gene ID (NCBI): 50649
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ARHGEF4, also named as KIAA1112 and Asef, acts as guanine nucleotide exchange factor (GEF) for RhoA and RAC1 GTPases. Binding of APC, ARHGEF4 may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion.(PMID: 10873612). This antibody is specific to ARHGEF4.