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ARRDC1 Rekombinanter Antikörper

ARRDC1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242396A5

Kat-Nr. : 84874-5-PBS

Synonyme

242396A5, Alpha-arrestin 1, arrestin domain containing 1, Arrestin domain-containing protein 1

Filter:
  • Western Blot (WB) analysis of various lysates using ARRDC1 Recombinant antibody (84874-5-RR)

    WB analysis using 84874-5-RR (same clone as 84874-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84874-5-RR (ARRDC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84874-5-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84874-5-PBS bindet in WB, Indirect ELISA ARRDC1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ARRDC1 fusion protein Ag15341
Vollständiger Name arrestin domain containing 1
Berechnetes Molekulargewicht 433 aa, 46 kDa
Beobachtetes Molekulargewicht46-50 kDa
GenBank-ZugangsnummerBC032346
Gene symbol ARRDC1
Gene ID (NCBI) 92714
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ARRDC1, or Arrestin-Domain Containing Protein 1, is a protein that plays a significant role in the formation and release of extracellular vesicles, specifically a subtype known as ARMMs (Arrestin-Domain Containing Protein 1-mediated microvesicles). ARRDC1 is localized to the cytosolic side of the plasma membrane and recruits the ESCRT-I complex protein TSG101 to initiate outward membrane budding. This protein is also involved in the regulation of protein cargo and release of extracellular vesicles, including both exosomes and ectosomes. The absence of ARRDC1 can lead to changes in the protein cargo within these vesicles, indicating its importance in the sorting and packaging process.