ASCC2 Rekombinanter Antikörper
ASCC2 Rekombinant Antikörper für Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
250566B11
Kat-Nr. : 86086-2-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
86086-2-PBS bindet in Indirect ELISA ASCC2 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | ASCC2 fusion protein Ag2100 |
| Vollständiger Name | activating signal cointegrator 1 complex subunit 2 |
| Berechnetes Molekulargewicht | 757 aa, 86 kDa |
| Beobachtetes Molekulargewicht | 90-100 kDa |
| GenBank-Zugangsnummer | BC025368 |
| Gene symbol | ASCC2 |
| Gene ID (NCBI) | 84164 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
ASCC2, also known as ASC1p100, is a subunit of the activating signal cointegrator 1 complex. ASCC2 plays a role in DNA damage repair as a component of the ASCC complex, recruiting ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Additionally, it is part of the ASC-1 complex that enhances NF-kappa-B, SRF, and AP1 transactivation(PMID: 29144457, 12077347).
