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ASCL1 Polyklonaler Antikörper

ASCL1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23751-1-PBS

Synonyme

Achaete-scute homolog 1, ASH1, ASH-1, bHLHa46, Class A basic helix-loop-helix protein 46

Filter:
  • Western Blot (WB) analysis of various lysates using ASCL1 Polyclonal antibody (23751-1-AP)

    WB analysis using 23751-1-AP (same clone as 23751-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23751-1-AP (ASCL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23751-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using ASCL1 Polyclonal antibody (23751-1-AP)

    IHC staining of human brain using 23751-1-AP (same clone as 23751-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 23751-1-AP (ASCL1 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 23751-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

23751-1-PBS bindet in WB, IHC, Indirect ELISA ASCL1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ASCL1 fusion protein Ag19360
Vollständiger Name achaete-scute complex homolog 1 (Drosophila)
Berechnetes Molekulargewicht 25 kDa
Beobachtetes Molekulargewicht25 kDa
GenBank-ZugangsnummerBC003134
Gene symbol ASCL1
Gene ID (NCBI) 429
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.