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ASL Monoklonaler Antikörper

ASL Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1G9H3

Kat-Nr. : 67692-1-PBS

Synonyme

argininosuccinate lyase, Arginosuccinase, ASAL, ASL

Filter:
  • Western Blot (WB) analysis of various lysates using ASL Monoclonal antibody (67692-1-Ig)

    WB analysis using 67692-1-Ig (same clone as 67692-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67692-1-Ig (ASL antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67692-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of LNCaP cells using ASL Monoclonal antibody (67692-1-Ig)

    WB analysis of LNCaP using 67692-1-Ig (same clone as 67692-1-PBS)

    LNCaP cells were subjected to SDS PAGE followed by western blot with 67692-1-Ig (ASL antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67692-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of K-562 cells using ASL Monoclonal antibody (67692-1-Ig)

    WB analysis of K-562 using 67692-1-Ig (same clone as 67692-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 67692-1-Ig (ASL antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67692-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67692-1-PBS bindet in WB, Indirect ELISA ASL und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen ASL fusion protein Ag30517
Vollständiger Name argininosuccinate lyase
Berechnetes Molekulargewicht 55 kDa
Beobachtetes Molekulargewicht50 kDa
GenBank-ZugangsnummerBC008195
Gene symbol ASL
Gene ID (NCBI) 435
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Argininosuccinate lyase (ASL), one of the significant UC enzymes, catalyzes argininosuccinate cleavage to generate arginine and fumarate. Arginine is then catalyzed by arginase to ornithine and polyamines, which are found to promote cancer cell proliferation and growth. Importantly, ASL ectopic expression is closely associated with poor prognosis of colorectal cancer, hepatocellular. ASL is a member of the aspartase/fumarase superfamily. Enzymes of this superfamily share similar tetrameric structure and active site, though the sequence identities between different members are quite low (less than 20%). Members of this superfamily have been recognised as drug targets for microbial infections. ASL is a 464-amino-acid enzyme with a molecular mass of 49.7 kDa. (PMID: 22386318 PMID: 31018905)