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ASXL1 Polyklonaler Antikörper

ASXL1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16803-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using ASXL1 Polyclonal antibody (16803-1-AP)

    WB analysis using 16803-1-AP (same clone as 16803-1-PBS)

    Various lysates were subjected to Tris-acetate gel system followed by western blot with 16803-1-AP (ASXL1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16803-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

16803-1-PBS bindet in WB, Indirect ELISA ASXL1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ASXL1 fusion protein Ag10290
Vollständiger Name additional sex combs like 1 (Drosophila)
Berechnetes Molekulargewicht84aa,10 kDa; 1541aa,165 kDa
Beobachtetes Molekulargewicht~200 kDa
GenBank-ZugangsnummerBC064984
Gene symbol ASXL1
Gene ID (NCBI) 171023
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Additional sex combs-like 1 (ASXL1) is a member of the ASXL family, which is involved in epigenetic regulation. It is one of the mammalian Asx homologs. Mutations in the ASXL1 gene are frequently found in myeloid neoplasms, breast cancers and prostate cancers (PMID: 30013160; PMID: 22436456; PMID: 26470845). In patients with myeloid malignancies, ASXL1 mutations are mostly heterozygous frameshift or nonsense mutations that result in C-terminal truncation (PMID: 30982744; PMID: 26095772; PMID: 32683582; PMID: 29643185).