ASXL2 Polyklonaler Antikörper

ASXL2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27229-1-PBS

Synonyme

Additional sex combs-like protein 2, ASXH2, KIAA1685

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  WB analysis using 27229-1-AP (same clone as 27229-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27229-1-AP (ASXL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27229-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

27229-1-PBS bindet in WB, Indirect ELISA ASXL2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ASXL2 fusion protein Ag24402
• Vollständiger Name: additional sex combs like 2 (Drosophila)
• Berechnetes Molekulargewicht: 154 kDa
• Beobachtetes Molekulargewicht: 154-230 kDa
• GenBank-Zugangsnummer: BC042999
• Gene symbol: ASXL2
• Gene ID (NCBI): 55252
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ASXL2 is an epigenetic regulator associated with various tumors including colorectal cancer, breast cancer, and myeloid leukemia. ASXL1, ASXL2 and ASXL3 are human homologs of Drosophila Asx (Additional sex combs) and function as epigenetic regulators through recruitment of Polycomb group repressor complexes (PRC) and Trithorax group activator complexes. ASXL proteins can interact with BAP1, NCOA1, EZH2, WTIP and nuclear receptors, which suggests diverse functions of ASXL family members in epigenetic and transcriptional regulation. (PMID: 30093396, PMID: 34692512)