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ATP2B1 Polyklonaler Antikörper

ATP2B1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30035-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using ATP2B1 Polyclonal antibody (30035-1-AP)

    WB analysis using 30035-1-AP (same clone as 30035-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30035-1-AP (ATP2B1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30035-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human colon tissue using ATP2B1 Polyclonal antibody (30035-1-AP)

    IHC staining of human colon using 30035-1-AP (same clone as 30035-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30035-1-AP (ATP2B1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30035-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using ATP2B1 Polyclonal antibody (30035-1-AP)

    IHC staining of human pancreas cancer using 30035-1-AP (same clone as 30035-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 30035-1-AP (ATP2B1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30035-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30035-1-PBS bindet in WB, IHC, Indirect ELISA ATP2B1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ATP2B1 fusion protein Ag32423
Vollständiger Name ATPase, Ca++ transporting, plasma membrane 1
Berechnetes Molekulargewicht135 kDa
Beobachtetes Molekulargewicht130-180 kDa
GenBank-ZugangsnummerNM_001001323.1
Gene symbol ATP2B1
Gene ID (NCBI) 490
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ATPase plasma membrane Ca2+ transporting 1 (ATP2B1, also known as plasma membrane Ca2+ pump isoform 1; PMCA1) belongs to the family of ATP-driven calmodulin-dependent Ca2+ pumps that participate in the regulation of intracellular free Ca2+ (PMID:35358416). The ATP2B1 contents of extracellular vesicles are increased in prostate cancer treated with enzalutamide and are negatively regulated by androgen receptors (PMID:29105980). ATP2B1 plays an important role in the prognosis of cholangiocarcinoma. Furthermore, ATP2B1 plays an important role in the prognosis of cholangiocarcinoma and can be a prognostic factor for cholangiocarcinoma (PMID:35875160).