ATP2B3/PMCA3 Polyklonaler Antikörper

ATP2B3/PMCA3 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31692-1-AP

Synonyme

ATP2B3, PMCA3

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  WB analysis using 31692-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31692-1-AP (ATP2B3/PMCA3 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 31692-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31692-1-AP (ATP2B3/PMCA3 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: bei 37°C inkubiertes Maushirngewebe, 37°C incubated rat brain tissue

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

31692-1-AP bindet in WB, ELISA ATP2B3/PMCA3 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ATP2B3/PMCA3 fusion protein Ag35923
• Vollständiger Name: ATPase, Ca++ transporting, plasma membrane 3
• Beobachtetes Molekulargewicht: 134 kDa
• GenBank-Zugangsnummer: BC047580
• Gene symbol: ATP2B3
• Gene ID (NCBI): 492
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ATP2B3 also known as PMCA3, belongs to the family of P-type primary ion transport ATPases. ATP2B3 uses ATP as an energy source to transport cytosolic Ca2+ ions across the plasma membrane to the extracellular compartment. ATP2B3 is highly expressed in the brain and cerebellum and is important in regulating neuronal Ca2+. Mutations in ATP2B3 are associated with X-linked spinocerebellar ataxia-1 (PMID: 25953895, 22912398).