ATP6V0D2 Polyklonaler Antikörper

ATP6V0D2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33364-1-PBS

Synonyme

ATP6, ATP6D2, V-ATPase subunit d 2, VMA6, V-type proton ATPase subunit d 2

---

• 

  WB analysis using 33364-1-AP (same clone as 33364-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 33364-1-AP (ATP6V0D2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33364-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

33364-1-PBS bindet in WB, Indirect ELISA ATP6V0D2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ATP6V0D2 fusion protein Ag38739
• Vollständiger Name: ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
• Berechnetes Molekulargewicht: 40 kDa
• Beobachtetes Molekulargewicht: 40 kDa
• GenBank-Zugangsnummer: BC065207
• Gene symbol: ATP6V0D2
• Gene ID (NCBI): 245972
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ATP6V0D2 is a subunit of the vacuolar proton-translocating ATPase (V-ATPase) complex, which is responsible for acidifying intracellular compartments and the extracellular environment. This protein is crucial for maintaining the acidic environment necessary for various cellular processes, including bone resorption by osteoclasts (PMID: 19113919). ATP6V0D2 is also involved in the regulation of tumor-associated macrophages, where it influences tumor progression through the lactate/ATP6V0D2/HIF-2α axis (PMID: 30431439).