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ATXN2L Rekombinanter Antikörper

ATXN2L Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251578A9

Kat-Nr. : 86613-3-PBS

Synonyme

A2D, A2LG, A2LP, A2RP, ataxin 2 like

Filter:
  • Western Blot (WB) analysis of various lysates using ATXN2L Recombinant monoclonal antibody (86613-3-RR)

    WB analysis using 86613-3-RR (same clone as 86613-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86613-3-RR (ATXN2L antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86613-3-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of Jurkat cells using ATXN2L Recombinant monoclonal antibody (86613-3-RR)

    IF Staining of Jurkat using 86613-3-RR (same clone as 86613-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using ATXN2L antibody (86613-3-RR, Clone: 251578A9 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 86613-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86613-3-RR

    Affinity and Kinetic Characterization of 86613-3-RR

    Biolayer interferometry (BLl) kinetic assays of 86613-3-RR against Human ATXN2L were performed. The affinity constant is 1.78 nM.

Geprüfte Anwendungen

Produktinformation

86613-3-PBS bindet in WB, IF/ICC, Indirect ELISA ATXN2L und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ATXN2L fusion protein Ag20581
Vollständiger Name ataxin 2-like
Berechnetes Molekulargewicht 1062 aa, 112 kDa
Beobachtetes Molekulargewicht150 kDa
GenBank-ZugangsnummerBC082760
Gene symbol ATXN2L
Gene ID (NCBI) 11273
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ATXN2L is a paralog of Ataxin-2 (ATXN2) but without abnormal polyQ expended track, which is conserved in most of the ATXNs and drives the pathogenesis of neurodegeneration. It was reported that ATXN2L was widely expressed in immortalized cell lines, and ATXN2L-JAK2 fusion was found in CD4-positive T-cell lymphoma.