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AVEN Polyklonaler Antikörper

AVEN Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25846-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of MCF-7 cells using AVEN Polyclonal antibody (25846-1-AP)

    WB analysis of MCF-7 using 25846-1-AP (same clone as 25846-1-PBS)

    MCF-7 cells were subjected to SDS PAGE followed by western blot with 25846-1-AP (AVEN Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25846-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of K-562 cells using AVEN Polyclonal antibody (25846-1-AP)

    WB analysis of K-562 using 25846-1-AP (same clone as 25846-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 25846-1-AP (AVEN Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25846-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25846-1-PBS bindet in WB, Indirect ELISA AVEN und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen AVEN fusion protein Ag23020
Vollständiger Name apoptosis, caspase activation inhibitor
Berechnetes Molekulargewicht 39 kDa
Beobachtetes Molekulargewicht 50 kDa
GenBank-ZugangsnummerBC010488
Gene symbol AVEN
Gene ID (NCBI) 57099
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

AVEN (Apoptosis caspase activation inhibitor) is known to play a role in male and female germ cell development. AVEN protein has also been shown to inhibit the mitochondrial apoptosis pathway by binding to and inhibiting the self-association of proapoptotic APAF-1, as well as binding to and enhancing antiapoptotic BCL-xL activity. AVEN has also recently been shown to function as an activator of the cell cycle-regulating ATM kinase in the DNA damage response pathway. Molecular weight of this protein detected by WB is 50 kDa (PMID: 22751129).