Alpha-2-Macroglobulin Rekombinanter Antikörper
Alpha-2-Macroglobulin Rekombinant Antikörper für WB, IF/ICC, FC (Intra), Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, IF/ICC, FC (Intra), Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
241649D2
Kat-Nr. : 84347-5-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
84347-5-PBS bindet in WB, IF/ICC, FC (Intra), Indirect ELISA Alpha-2-Macroglobulin und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | Fusionsprotein |
Vollständiger Name | alpha-2-macroglobulin |
Berechnetes Molekulargewicht | 163kDa |
Beobachtetes Molekulargewicht | 185 kDa |
GenBank-Zugangsnummer | NM_000014.6 |
Gene symbol | Alpha 2 Macroglobulin |
Gene ID (NCBI) | 2 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein A purfication |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Alpha-2-Macroglobulin, also known as α2-macroglobulin (α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer's disease.