Alpha-2-Macroglobulin Rekombinanter Antikörper

Alpha-2-Macroglobulin Rekombinant Antikörper für WB, IF/ICC, FC (Intra), Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, FC (Intra), Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241649D2

Kat-Nr. : 84347-5-PBS

Synonyme

A2M, 241649D2, Alpha-2-M, Alpha 2M, alpha 2 macroglobulin



Geprüfte Anwendungen

Produktinformation

84347-5-PBS bindet in WB, IF/ICC, FC (Intra), Indirect ELISA Alpha-2-Macroglobulin und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Fusionsprotein
Vollständiger Name alpha-2-macroglobulin
Berechnetes Molekulargewicht163kDa
Beobachtetes Molekulargewicht 185 kDa
GenBank-ZugangsnummerNM_000014.6
Gene symbol Alpha 2 Macroglobulin
Gene ID (NCBI) 2
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Alpha-2-Macroglobulin, also known as α2-macroglobulin (α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer's disease.