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Alpha Synuclein Polyklonaler Antikörper

Alpha Synuclein Polyklonal Antikörper für WB, IHC, IF/ICC, IF-Fro, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, IF-Fro, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10842-1-PBS

Synonyme

1, a-synuclein, SNCA, Alpha-synuclein, NACP



Geprüfte Anwendungen

Produktinformation

10842-1-PBS bindet in WB, IHC, IF/ICC, IF-Fro, ELISA Alpha Synuclein und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Alpha Synuclein fusion protein Ag1285
Vollständiger Name synuclein, alpha (non A4 component of amyloid precursor)
Berechnetes Molekulargewicht 14 kDa
Beobachtetes Molekulargewicht 15-19 kDa
GenBank-ZugangsnummerBC013293
Gene symbol Alpha Synuclein
Gene ID (NCBI) 6622
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Alpha Synuclein (α-syn) is a 14-19 kDa phosphoprotein that is primarily localize to the presynaptic terminals of mature neurons, where it is involved in synaptic function and plasticity. Α-syn has drawn intense interest ever since the late 1990s, when the first α-synuclein missense mutation was identified as a cause of familial Parkinson's disease (PD). Aggregated and hyper-phosphorylated forms of α-syn protein are the pathological hallmark of Lewy body disease, which includes Parkinson's disease (PD), diffuse Lewy body disease (DLBD), and Lewy body variant of Alzheimer's disease (LBV). This antibody can recognize all the isoforms of α-syn.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
IHC protocol for Alpha Synuclein antibody 10842-1-PBSProtokoll herunterladenl
STANDARD-PROTOKOLLE
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