Amylin Polyklonaler Antikörper

Amylin Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22305-1-PBS

Synonyme

IAPP, DAP, Diabetes associated peptide, Diabetes-associated peptide, islet amyloid polypeptide

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  IHC staining of human pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 22305-1-AP (Amylin Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 22305-1-AP (Amylin Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

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  IHC staining of rat pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat pancreas tissue slide using 22305-1-AP (Amylin antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat pancreas tissue slide using 22305-1-AP (Amylin antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 22305-1-AP (Amylin antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse pancreas using 22305-1-AP (same clone as 22305-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 22305-1-AP (Amylin antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22305-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

22305-1-PBS bindet in IHC, Indirect ELISA Amylin und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: islet amyloid polypeptide
• Berechnetes Molekulargewicht: 10 kDa
• GenBank-Zugangsnummer: NM_000415
• Gene symbol: Amylin
• Gene ID (NCBI): 3375
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-affinitätsgereinigt
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring a tumor of the pancreas that is derived from beta cells and secretes INS. IAPP is co-secreted with INS by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.