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Angiopoietin 1 Monoklonaler Antikörper

Angiopoietin 1 Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3C4A3

Kat-Nr. : 68618-1-PBS

Synonyme

ANGPT1, ANG-1, ANG1, ANG 1, AGPT

Filter:
  • Western Blot (WB) analysis of various lysates using Angiopoietin 1 Monoclonal antibody (68618-1-Ig)

    WB analysis using 68618-1-Ig (same clone as 68618-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68618-1-Ig (ANGPT1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68618-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HUVEC cells using Angiopoietin 1 Monoclonal antibody (68618-1-Ig)

    IF Staining of HUVEC using 68618-1-Ig (same clone as 68618-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed HUVEC cells using Angiopoietin 1 antibody (68618-1-Ig, Clone: 3C4A3 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 68618-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68618-1-PBS bindet in WB, IF/ICC, Indirect ELISA Angiopoietin 1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Angiopoietin 1 fusion protein Ag18829
Vollständiger Name angiopoietin 1
Berechnetes Molekulargewicht 498 aa, 58 kDa
Beobachtetes Molekulargewicht70 kDa, 55 kDa
GenBank-ZugangsnummerBC152411
Gene symbol Angiopoietin 1
Gene ID (NCBI) 284
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Angiopoietin 1 is a 70-kDa secreted glycoprotein generated from vascular mural cells, pericytes, and certain other cells. Angiopoietin 1 participates in vascular differentiation through angiogenesis, which is the process of the growth and remodelling of existing vessels. Angiopoietin 1 is also involved in the maintenance and turnover of blood vessels in mature animals. Angiopoietin 1 binds to and activates the TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation, playing an important role in the regulation of angiogenesis. Overexpression of Angiopoietin 1 has been proven to occur in malignant glioblastoma, neuroblastoma, non-small cell lung cancer, and other tumors.