Apolipoprotein A II/APOA2 Monoklonaler Antikörper

Apolipoprotein A II/APOA2 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1G1A2

Kat-Nr. : 66773-1-PBS

Synonyme

APOA2, apolipoprotein A II, ApoA-II, Apo-AII, ApoA II

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  WB analysis of human plasma using 66773-1-Ig (same clone as 66773-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 66773-1-Ig (Apolipoprotein A II/APOA2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66773-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 66773-1-Ig (same clone as 66773-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66773-1-Ig (Apolipoprotein A II/APOA2 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66773-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 66773-1-Ig (same clone as 66773-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 66773-1-Ig (Apolipoprotein A II antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66773-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66773-1-PBS bindet in WB, IHC, Indirect ELISA Apolipoprotein A II/APOA2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Apolipoprotein A II/APOA2 fusion protein Ag9863
• Vollständiger Name: apolipoprotein A-II
• Berechnetes Molekulargewicht: 100 aa, 11 kDa
• Beobachtetes Molekulargewicht: 8-11 kDa
• GenBank-Zugangsnummer: BC005282
• Gene symbol: APOA2
• Gene ID (NCBI): 336
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Apolipoprotein A-II (APOA2) is a major component of high density lipoprotein (HDL) and it plays an important role in directing the fate of lipid metabolism among HDL. It is primarily synthesized by liver. The predicted MW of ApoA2 is 11 kDa, while the mature form is smaller (7-10 kDa) since the signal peptide was cleaved. In humans, most of circulating apoA2 exist as dimer. Five types of APOA2 dimer exist: homodimer apoA2-ATQ/ATQ, heterodimer apoA2-ATQ/AT, homodimer apoA2-AT/AT, apoA2-AT/A, and apoA2-A/A. ApoA2 isoforms are considered to be some of the most promising serum/plasma biomarkers for aiding the early detection of pancreatic cancer. (PMID: 29081441, 29481802)