Aquaporin 4 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

Aquaporin 4 Polyklonal Antikörper für IF-P

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, IF-P

Konjugation

CoraLite® Plus 647 Fluorescent Dye

Publikationen(4)

Rezensionen (2)

Kat-Nr. : CL647-16473

Synonyme

AQP 4, AQP4, aquaporin 4, HMIWC2, MIWC, WCH4

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  IF Staining of mouse brain using CL647-16473

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite® Plus 647 Aquaporin 4 antibody (CL647-16473) at dilution of 1:200.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IF-P: Maushirngewebe

Empfohlene Verdünnung

• Immunfluoreszenz (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• IHC: See 1 publications below
• IF: See 3 publications below

Produktinformation

CL647-16473 bindet in IHC, IF-P Aquaporin 4 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Aquaporin 4 fusion protein Ag9561
• Vollständiger Name: Aquaporin 4
• Berechnetes Molekulargewicht: 323 aa, 35 kDa
• Beobachtetes Molekulargewicht: 35-37 kDa, 32-34 kDa
• GenBank-Zugangsnummer: BC022286
• Gene symbol: Aquaporin 4
• Gene ID (NCBI): 361
• Konjugation: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Lagerungsbedingungen: Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Aquaporins are specialized water transport channels in plasma membranes of water-permeable tissues. Aquaporin-4 (AQP4) is the most abundant water channel in the human central nervous system and is important to fluid movements in brain. Aquaporin-4 exists as two isoforms, a long (M1) isoform with translation initiation at Met-1, and a shorter (M23) isoform with translation initiation at Met-23, with molecular weights around 35-37 kDa and 32-34 kDa, respectively.

Publikationen

Species	Application	Title
mouse	IF	Adv Mater; Noninvasive Optogenetics Realized by iPSC-Derived Tentacled Carrier in Alzheimer's Disease Treatment; Authors - Yuewen Zhai
	IHC	Front Neurosci; Stress in utero: prenatal dexamethasone exposure causes greater structural gliovascular alterations in female offspring than in males; Authors - Magda Ferreira-Rodrigues
mouse	IF	J Clin Invest; APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading; Authors - Chanung Wang
mouse	IF	Cell Rep; Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease; Authors - Min Yu

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.

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FH

Aito (Verified Customer) (05-27-2025)

Aquaporin 4 and DAPI in a slide of human glioblastoma sample.

• Applications: Immunofluorescence
• Primary Antibody Dilution: 1/100
• Cell Tissue Type: human brain glioblastoma

CL Plus 647 Aquaporin 4 Antibody Immunofluorescence validation (1/100 dilution) in human brain glioblastoma (Cat no:CL647-16473)

FH

Vanessa (Verified Customer) (09-27-2023)

Works Perfectly!

• Applications: Immunohistochemistry, Immunofluorescence
• Primary Antibody Dilution: 1:200
• Cell Tissue Type: Brain