Beta-2-Microglobulin Rekombinanter Antikörper

Beta-2-Microglobulin Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250172F11

Kat-Nr. : 98442-2-PBS

Synonyme

B2m, beta 2 microglobulin

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  FC experiment of mouse splenocytes using 98442-2-RR (same clone as 98442-2-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse Beta-2-Microglobulin Rabbit RecAb (98442-2-RR, Clone: 250172F11) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L)(red). Cells were not fixed. This data was developed using the same antibody clone with 98442-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98442-2-PBS bindet in FC Beta-2-Microglobulin und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Beta-2-Microglobulin fusion protein Eg3086
• Vollständiger Name: beta-2 microglobulin
• Berechnetes Molekulargewicht: 14 kDa
• GenBank-Zugangsnummer: NM_009735.3
• Gene symbol: B2m
• Gene ID (NCBI): 12010
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions due to shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.