B7-H3/CD276 Rekombinanter Antikörper

B7-H3/CD276 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Biotin

CloneNo.

230305A10

Kat-Nr. : Biotin-FcA98017

Synonyme

CD276, 230305A10, 4Ig-B7-H3, B7 H3, B7 homolog 3

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  FC experiment of human monocyte-derived dendritic using Biotin-FcA98017

  1x10^6 human monocyte-derived dendritic cells were surface stained with 0.25 ug Biotin Anti-Human B7-H3/CD276 Rabbit RecAb (Biotin-FcA98017, Clone: 230305A10) (red) or 0.25 ug FcZero-rAb™ Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9), and PE-conjugated streptavidin. Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane, aus Monozyten gewonnene dendritische Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

Biotin-FcA98017 bindet in FC B7-H3/CD276 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: B7-H3/CD276 fusion protein Eg0075
• Vollständiger Name: CD276 molecule
• Berechnetes Molekulargewicht: 57 kDa
• GenBank-Zugangsnummer: NM_001024736
• Gene symbol: CD276
• Gene ID (NCBI): 80381
• Konjugation: Biotin
• Excitation/Emission maxima wavelengths: -
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).