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B7-H4 Rekombinanter Antikörper

B7-H4 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

243033D6

Kat-Nr. : 82850-6-PBS

Synonyme

VTCN1, B7 H4, B7 homolog 4, B7h.5, B7H4

Filter:
  • Western Blot (WB) analysis of SK-BR-3 cells using B7-H4 Recombinant antibody (82850-6-RR)

    WB analysis of SK-BR-3 using 82850-6-RR (same clone as 82850-6-PBS)

    SK-BR-3 cells were subjected to SDS PAGE followed by western blot with 82850-6-RR (VTCN1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82850-6-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

82850-6-PBS bindet in WB, Indirect ELISA B7-H4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen B7-H4 fusion protein Eg0098
Vollständiger Name V-set domain containing T cell activation inhibitor 1
Berechnetes Molekulargewicht282 aa, 31 kDa
Beobachtetes Molekulargewicht65 kDa
GenBank-ZugangsnummerNM_024626
Gene symbol B7-H4
Gene ID (NCBI) 79679
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

B7-H4, also named VTCN1, B7X, or B7S1, is a single-pass type I membrane protein, which contains two immunoglobulin-like domains and belongs to the immunoglobulin superfamily. B7-H4 negatively regulates T-cell mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. B7-H4 is over-expressed in many cancers, including breast, ovarian, endometrial, renal cell and non-small-cell lung cancers. The predicted molecular weight of B7‑H4 is 31 kDa. The glycosylated B7‑H4 is 50 to 80 kDa, and the non-glycosylated form is 28 kDa.