B7-H4 Rekombinanter Antikörper

B7-H4 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Ratte

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250392E12

Kat-Nr. : 98552-2-RR

Synonyme

B7H4, B7S1, B7x, V-set domain-containing T-cell activation inhibitor 1, Vtcn1

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  FC experiment of Transfected HEK-293T using 98552-2-RR

  1x10^6 HEK-293T cells (left) or B7-H4 transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Rat B7-H4 Rabbit RecAb (98552-2-RR, Clone: 250392E12) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  FC experiment of Transfected HEK-293T using 98552-2-RR

  1x10^6 HEK-293T cells (left) or B7-H4 transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Rat B7-H4 Rabbit RecAb (98552-2-RR, Clone:250392E12) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Transfected HEK-293T cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98552-2-RR bindet in FC B7-H4 und zeigt Reaktivität mit Ratten

• Getestete Reaktivität: Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: B7-H4 fusion protein Eg3230
• Vollständiger Name: V-set domain containing T cell activation inhibitor 1
• Berechnetes Molekulargewicht: 31 kDa
• GenBank-Zugangsnummer: NM_001024244.1
• Gene symbol: Vtcn1
• Gene ID (NCBI): 295322
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

B7-H4, also named VTCN1, B7X, or B7S1, is a single-pass type I membrane protein, which contains two immunoglobulin-like domains and belongs to the immunoglobulin superfamily. B7-H4 negatively regulates T-cell mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. B7-H4 is over-expressed in many cancers, including breast, ovarian, endometrial, renal cell and non-small-cell lung cancers.