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B7-H6 Polyklonaler Antikörper

B7-H6 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27428-1-PBS

Synonyme

B7H6, NCR3LG1, B7 H6, B7 homolog 6, Natural cytotoxicity triggering receptor 3 ligand 1

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  • Western Blot (WB) analysis of HEK-293 cells using B7-H6 Polyclonal antibody (27428-1-AP)

    WB analysis of HEK-293 using 27428-1-AP (same clone as 27428-1-PBS)

    WB result of B7-H6 antibody (27428-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-B7-H6 transfected HEK-293 cells. This data was developed using the same antibody clone with 27428-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using B7-H6 Polyclonal antibody (27428-1-AP)

    WB analysis using 27428-1-AP (same clone as 27428-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27428-1-AP (B7H6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27428-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27428-1-PBS bindet in WB, Indirect ELISA B7-H6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen B7-H6 fusion protein Ag26532
Vollständiger Name hypothetical protein DKFZp686O24166
Berechnetes Molekulargewicht51 kDa
Beobachtetes Molekulargewicht75-80 kDa
GenBank-ZugangsnummerBC136800
Gene symbol B7H6
Gene ID (NCBI) 374383
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

B7-H6, also known as NCR3LG1, is a member of the B7 family of immunoreceptors. It is a 454-aa-long type I transmembrane protein consisting of an extracellular region, a transmembrane segment, and a cytoplasmic domain which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), an SH2-binding domain, and an SH3-binding motif. B7-H6 triggers NKp30-mediated activation of human NK cells (PMID: 19528259). It has been reported that B7H6 is expressed in various types of tumor cells and plays a prominent role in natural killer cell immunosurveillance (PMID: 35697295). The apparent molecular weight of B7-H6 is larger than the calculated molecular weight of 51 kDa due to glycosylation (PMID: 19528259).