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BAFF Rekombinanter Antikörper

BAFF Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242006E4

Kat-Nr. : 84541-3-PBS

Synonyme

242006E4

Filter:
  • Western Blot (WB) analysis of various lysates using BAFF Recombinant antibody (84541-3-RR)

    WB analysis using 84541-3-RR (same clone as 84541-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84541-3-RR (BAFF antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84541-3-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of U-937 cells using BAFF Recombinant antibody (84541-3-RR)

    WB analysis of U-937 using 84541-3-RR (same clone as 84541-3-PBS)

    U-937 cells were subjected to SDS PAGE followed by western blot with 84541-3-RR (BAFF antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84541-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84541-3-PBS bindet in WB, Indirect ELISA BAFF und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen FusionProtein
Vollständiger Name tumor necrosis factor (ligand) superfamily, member 13b
Berechnetes Molekulargewicht34kd
Beobachtetes Molekulargewicht 32kd, 17kd
GenBank-ZugangsnummerNM_033622
Gene symbol Tnfsf13b
Gene ID (NCBI) 24099
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BAFF (B-cell-activating factor), also called Tnfsf13b (Tumor necrosis factor ligand superfamily member 13B) and CD257, is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in stimulating B- and T-cell function and the regulation of humoral immunity. A third B-cell-specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response (PMID: 12867412). BAFF cleaved into 2 chains: membrane form is 32-35 kDa; soluble form is 17 kDa.