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BAG1L-specific Polyklonaler Antikörper

BAG1L-specific Polyklonal Antikörper für IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16148-1-PBS

Synonyme

Filter:
  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using BAG1L-specific Polyclonal antibody (16148-1-AP)

    IF Staining of HepG2 using 16148-1-AP (same clone as 16148-1-PBS)

    Immunofluorescent analysis of HepG2 cells, using BAG1 antibody 16148-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). This data was developed using the same antibody clone with 16148-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

16148-1-PBS bindet in IF/ICC, Indirect ELISA BAG1L-specific und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name BCL2-associated athanogene
Berechnetes Molekulargewicht 39 kDa
GenBank-ZugangsnummerNM_004323
Gene symbol BAG1
Gene ID (NCBI) 573
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BAG1 has been identified that modulates gene transcription through poorly defined mechanisms. Four isoforms of the BAG1 protein (BAG1S, BAG1, BAG1M, and BAG1L) can be produced from a common mRNA by use of alternative translation initiation sites, including a non-canonical CTG codon in one instance. The longest, BAG1L (Mr ~50K), contains a nuclear localization signal (NLS) and resides in the nucleus, whereas BAG1M (Mr ~46K) has an incomplete NLS and distributes mainly in cytosol, unless dragged into the nucleus through interactions with other. Distribution of BAG1S(p33) is not clear yet. This antibody can recognize BAG1L and BAG1V.