BAK Rekombinanter Antikörper

BAK Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242458D10

Kat-Nr. : 85200-1-PBS

Synonyme

BAK1, 242458D10, Bcl-2 homologous antagonist/killer, Bcl2-L-7, Bcl-2-like protein 7

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  WB analysis using 85200-1-RR (same clone as 85200-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85200-1-RR (BAK antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85200-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85200-1-PBS bindet in WB, Indirect ELISA BAK und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: BCL2-antagonist/killer 1
• Berechnetes Molekulargewicht: 23 kDa
• Beobachtetes Molekulargewicht: 23-25 kDa
• GenBank-Zugangsnummer: BC004431
• Gene symbol: BAK1
• Gene ID (NCBI): 578
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The BAK encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.